I have a lot, but the most recent one I read and loved to bits is Bokurano. It is so deliciously twisted.
Just finished reading Tokyo Ghoul. It. Is. So. Good!
Hayao Miyazaki's work is breathtaking. He was the reason I was so interested in manga at a young age. I hope that his films also get more recognition including his work with Studio Ghibli. The first movie of his I watched was Ponyo and my favorite was either From Up on Poppy Hill or the Wind Rises.There's not a doubt as to what my favourite manga is; Hayao Miyazaki's Kaze no Tane no Nausicaa. He is an artist par excellence and his stories are always, without fail excellent, but Nausicaa takes it just that bit further. A science-fiction epic, ecological poetry, a pacifist magnum opus, a philosophical study of human mentality and the will to survive, take it as you wish, it's simply sublime.
Films and series-wise, there would obviously be all the Miyazaki greats-Nausicaa, Mononoke and Castle of Cagliostro are, for my part, the best, and Macross Plus, Vision of Escaflowne, Trigun and Tenchi Muyo are also excellent. I've just 'acquired' Haibane Renmei and have heard nothing but good reports about it, so I'll have to see how it goes.